Rebuilds skin structure
GHK-Cu activates fibroblasts to lay down new collagen and elastin and remodel the extracellular matrix — the scaffold your skin's firmness, bounce, and smoothness rest on. Fine lines soften as the architecture comes back.
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GHK-Cu/Epitalon
Skin + Cellular Renewal
New here? Use code WELCOME10 at checkout for 10% off your first order: $269/mo on a 1-month supply.
Anti-Aging
Dual-action blend for visible skin rejuvenation and cellular anti-aging.
$299 / month
Starting at $229/mo with 3-month supply + WELCOME10
- Stimulates collagen and elastin production
- May extend telomere length
- Improved skin firmness and elasticity
- Supports cellular longevity
- Reduces fine lines and wrinkles
Dosage3mg/mL (GHK-Cu) + 5mg/mL (Epitalon), 5mL vial
AdministrationSubcutaneous injection
Compounded in the U.S.A.
About
What is GHK-Cu/Epitalon?
GHK-Cu/Epitalon puts two anti-aging peptides in a single vial, working from opposite ends. GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a copper peptide that signals fibroblasts to rebuild collagen and elastin — the structural proteins skin firmness depends on — and remodels the extracellular matrix your skin sits on. Epitalon is a tetrapeptide that activates telomerase, the enzyme that protects and lengthens the telomere caps on your chromosomes.
Run together, you get visible rejuvenation (firmer, smoother, more even skin; softer fine lines; sometimes stronger hair and nails) layered on top of cellular protection (telomere maintenance, restored melatonin, more antioxidant defense). Anti-aging from the outside in and the inside out — what neither peptide does alone.
PeRx ships GHK-Cu/Epitalon fully reconstituted from an FDA-registered 503A pharmacy. No mixing — insulin syringes and a step-by-step guide arrive in the box. It is a subcutaneous injection, often run in cycles, on a provider-determined schedule.
Why do people explore GHK-Cu/Epitalon therapy?
GHK-Cu signals fibroblasts to build new collagen and elastin, rebuilding the structural proteins that firmness and bounce depend on.
Epitalon activates telomerase to protect the caps on your chromosomes, slowing the cellular clock that drives biological aging.
Fine lines and wrinkles soften as GHK-Cu remodels the extracellular matrix, the scaffold your skin sits on.
GHK-Cu neutralizes oxidative damage at the cellular level, one of the primary drivers behind how fast you age.
Visible skin rejuvenation plus cellular longevity protection. Anti-aging from the outside in and the inside out in one vial.
Why people explore GHK-Cu/Epitalon
A clearer path forward.
Protects DNA at the telomere
Telomeres shorten with every cell division; too short, and cells stop replicating. Epitalon activates telomerase to maintain those caps, and restores pineal melatonin output along the way.
In human cell studies, Epitalon-treated cells showed ~33% telomere elongation and kept dividing past the 44th passage.
Outside-in and inside-out at once
Most anti-aging peptides hit one layer. This one rebuilds the surface (GHK-Cu) and protects the cellular machinery underneath (Epitalon) — visible results and longevity support from a single daily injection.
What it helps with
Designed for these concerns.
- Stimulates collagen and elastin production
- May extend telomere length
- Improved skin firmness and elasticity
- Supports cellular longevity
- Reduces fine lines and wrinkles
- Enhanced antioxidant activity
- Comprehensive anti-aging support
Ideal for
Those seeking comprehensive anti-aging · Adults wanting both visible and cellular rejuvenation · Individuals focused on longevity optimization · Those wanting skin improvement alongside cellular health
The science
How GHK-Cu/Epitalon works.
GHK-Cu activates collagen and elastin production for skin repair and firmness. Epitalon activates telomerase to maintain telomere length and slow cellular aging. Together they address both visible and cellular markers of aging.
01
Signal
GHK-Cu/Epitalon is given as a subcutaneous injection, often in cycles, on a provider-determined schedule.
02
Cellular response
GHK-Cu activates collagen and elastin production for skin repair and firmness. Epitalon activates telomerase to maintain telomere length and restores melatonin output. Together they address both visible and cellular markers of aging.
03
Outcome
Over the following weeks most people notice better skin hydration and texture first, plus subtle sleep and energy gains from Epitalon (weeks 1–3), then visibly firmer, smoother, more even skin (weeks 3–6), then deeper rejuvenation — elasticity, sometimes thicker hair and nails — with telomere support well established (weeks 6–12+). Many run periodic cycles.
Subcutaneous injectionCompounded in the U.S.A. at a 503A pharmacyProvider-prescribed
What the research shows
Backed by published science.
2 peptides
GHK-Cu (skin/collagen) + Epitalon (telomeres) in one vial
~33%
Telomere elongation seen with Epitalon in human cell studies
Collagen ↑
GHK-Cu out-produced vitamin C and retinoic acid in trials
25+ yrs
Of published research behind Epitalon
- GHK-Cu collagen synthesis well-documented
- Epitalon telomerase activation studied in Russian trials
- Complementary anti-aging mechanisms
- Both compounds well-tolerated independently
Lab tested medications
for quality & potency
Our medication is delivered from a state-licensed pharmacy in our network, right to your door when you need it.
Third-party quality control testing
Compounded in U.S. pharmacies
Lab tested for quality & potency
Our pharmacies perform third-party testing through FDA and DEA registered labs to run quality control checks for every compounded lot. They test four key characteristics associated with quality and safety.
Potency Test
PassedPerformed on every batch to confirm the active ingredient is present at the labeled concentration. Your vial contains exactly what it should.
Sterility Test
PassedTests for the presence of bacteria, fungi, and other microorganisms. Every batch is tested and must meet the requirements of USP 797.1.
Endotoxin Test
PassedScreens for bacterial endotoxins that can cause fever or adverse reactions. Every batch is tested and must not exceed the threshold limits defined in USP 85.
pH Test
PassedAssesses the acid/base balance to ensure minimal irritation upon injection and confirm the solution is within the correct range for subcutaneous administration.
What to expect
Your GHK-Cu/Epitalon timeline.
- 01
Week 1–3
Foundation
What you may notice: Skin may feel slightly more hydrated and supple. Energy and sleep quality may subtly improve as Epitalon begins regulating melatonin cycles.
What’s happening: GHK-Cu is signaling fibroblasts to ramp up collagen and elastin production. Epitalon is activating telomerase, beginning telomere protection at the chromosomal level.
- 02
Week 3–6
Visible changes begin
What you may notice: Skin texture improving. Fine lines softening. Complexion brighter and more even. GHK-Cu's collagen remodeling is producing visible changes.
What’s happening: Collagen remodeling is accelerating — the extracellular matrix is being restructured with new collagen fibers. Telomerase activity is sustained, actively maintaining telomere length during cell division.
- 03
Week 6–12
Full rejuvenation
What you may notice: Significant skin improvement: firmer, more elastic, more even-toned. Hair and nails may strengthen. Both peptides are delivering compounding benefits.
What’s happening: Cumulative collagen and elastin rebuilding is producing measurable improvements in skin firmness and elasticity. Telomere protection is well established.
- 04
Week 12+
Sustained anti-aging
What you may notice: Ongoing cellular protection. Skin quality maintained. Many people cycle in regular intervals for sustained longevity benefits.
What’s happening: Both pathways are delivering compounding results. GHK-Cu continues to maintain and rebuild skin structure; Epitalon continues to support telomere integrity. Many people adopt a cycling protocol for long-term use.
Comparison
GHK-Cu/Epitalon vs. GHK-Cu (standalone)
The combo adds telomere protection to GHK-Cu's skin work — here's the difference.
| GHK-Cu/Epitalon | GHK-Cu (standalone) | |
|---|---|---|
| Best for | Complete anti-aging — visible skin + cellular longevity | Skin rejuvenation, collagen, wound healing |
| How it works | Collagen rebuilding (GHK-Cu) + telomerase activation (Epitalon) | Copper-peptide collagen signaling and tissue remodeling |
| Scope | Surface-level skin + chromosomal/DNA protection | Surface-level tissue remodeling |
| Best if you want | Aging skin and longevity goals | A skin-quality focus — fine lines, firmness, healing |
| Can combine? | Yes — pairs well with NAD+, Thymosin Alpha-1 | Yes — pairs well with Epitalon, NAD+ |
What’s included
Everything you need to start safely.
From the moment you finish your assessment to your first dose, every step is handled by licensed providers and U.S. pharmacies.
New to self-injection? See the step-by-step guide- Provider evaluation and prescription
- Pharmacy-grade medication from an FDA-registered 503A pharmacy
- Insulin syringes and alcohol swabs
- Step-by-step administration guide
- FedEx Overnight cold-chain shipping
- On-demand messaging with your provider
FAQ
Common questions about GHK-Cu/Epitalon.
Patient reviews
What patients are saying.
No reviews yet. Be the first verified patient to share your experience.
This is not medical advice. Every patient's experience differs and not everyone qualifies for peptide therapy. All reviews are from verified PeRx patients and are published as submitted. Peptide therapy requires a valid prescription from a licensed provider.
Your safety, first
Important safety information.
- Generally well tolerated
- Possible injection site reactions
- Monitor thyroid function (Epitalon component)
- Requires licensed provider supervision
All prescriptions are issued by a licensed US provider after reviewing your intake.
Side effects, contraindications, and what to discuss with your provider before starting.
Read safety informationSupporting research
Selected studies.
A selection of peer-reviewed work on GHK-Cu/Epitalon. Browse the full literature on PubMed and Google Scholar for ongoing research.
GHK-Cu: collagen synthesis and skin remodeling
Pickart L, Margolina A. Int J Mol Sci. 2018;19(7):2047.Epitalon activates telomerase in human cells
Khavinson VK et al. Bull Exp Biol Med. 2003.Telomere length and biological aging
Cawthon RM et al. Lancet. 2003;361(9355):393–395.
The statements on this page have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The FDA does not review or approve compounded medications for safety or effectiveness. Off-label use must be prescribed and supervised by a licensed provider.
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Last updated April 2026
Medical disclaimer
The information provided on this page is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. Peptide therapy requires a valid prescription from a licensed healthcare provider. Individual results may vary. No specific outcomes are guaranteed.
The peptides on this site are not FDA-approved. They are compounded by licensed pharmacies under provider supervision. Certain peptides are prohibited by WADA and major sports organizations. Statements on this page have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.
Ready to start with GHK-Cu/Epitalon?
Take our 2-minute assessment. A licensed US provider reviews and, if appropriate, prescribes a protocol shipped to your door.
$299 / month
Starting at $229/mo with 3-month supply + WELCOME10