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KLOW Peptide Dosage: Chart, Frequency, Cycle

Nearly every KLOW dosage chart online describes an 80 mg research vial that someone mixes at their kitchen table. The KLOW a physician actually prescribes is a different product with different math. This is the dosing as written on the PeRx prescription: units on the syringe, days per week, weeks per cycle, and what the gray-market charts get wrong.

PeRx PeptidesReviewed by Dr. Cory Mellon, MD13 min readPublished
A 20-unit (0.2 mL) draw of KLOW on a U-100 insulin syringe delivers 3.8 mg of peptide across BPC-157, GHK-Cu, KPV, and TB-500.
A 20-unit (0.2 mL) draw of KLOW on a U-100 insulin syringe delivers 3.8 mg of peptide across BPC-157, GHK-Cu, KPV, and TB-500.

Key Takeaways

  • Prescribed KLOW dosage at PeRx is 20 units (0.2 mL) under the skin, Monday through Friday, for 6 weeks, followed by 6 weeks off before restarting if still needed.
  • Each 20-unit dose delivers 0.6 mg BPC-157, 2.0 mg GHK-Cu, 0.6 mg KPV, and 0.6 mg TB-500, which is 3.8 mg of peptide total. That works out to 19 mg per week and roughly 114 mg over a full 6-week course.
  • The vial ships ready to use with no reconstitution needed. There is no mixing step and no concentration math; you draw to the 20-unit line on an insulin syringe.
  • The 80 mg research blend that dominates search results uses a 50/10/10/10 ratio and assumes the buyer mixes the product. Its charts describe a different product and do not transfer to the prescribed vial.
  • The July 2026 FDA advisory committee recommended BPC-157, KPV, and TB-500 for the 503A bulks list by 8 to 6 votes. The recommendation is non-binding, no rule has followed, and injectable GHK-Cu is not scheduled for review until February 2027. None of that changed the dose.

KLOW Dosage Quick Facts

Dose

20 units (0.2 mL) subcutaneously

Frequency

Once daily, Monday through Friday

Cycle

6 weeks on, 6 weeks off before restarting

Per injection

0.6 mg BPC-157, 2.0 mg GHK-Cu, 0.6 mg KPV, 0.6 mg TB-500 (3.8 mg total)

Vial

5 mL at 3/10/3/3 mg per mL, ready to use, about 25 doses

Placement

As close to the injury site as possible, rotating

Last reviewed

August 27, 2026

What Is in the Prescribed Vial

Any KLOW dosage number is meaningless until you know the concentration behind it, and this is where most of the confusion starts. KLOW is not a single molecule with a fixed strength. It is a name for a four-peptide combination, and different suppliers put different amounts of each peptide in the vial. The prescribed version dispensed through PeRx comes from a 503A compounding pharmacy at 3 mg BPC-157, 10 mg GHK-Cu, 3 mg KPV, and 3 mg TB-500 per mL, in a 5 mL vial. Total peptide content in the vial is 95 mg, and more than half of it by weight is GHK-Cu.

That vial arrives in solution. It ships fully reconstituted and ready to use, refrigerated, with insulin syringes and swabs in the box. This one fact removes almost every step the online calculators exist to solve. You are not deciding how much diluent to add or converting milligrams into units based on a concentration you chose. The pharmacy chose it, the label states it, and the prescription tells you how many units to draw. If you want the background on the four components, the BPC-157 guide covers the peptide that anchors the blend and What Is KPV covers the one most people have never heard of.

KLOW Dosage Chart

The chart below is the prescribed protocol, laid out so you can see how the single syringe number turns into per-peptide milligrams, weekly totals, and a full course. Every row derives from the same two figures: 20 units on a U-100 insulin syringe equals 0.2 mL, and the concentration is 3/10/3/3 mg per mL.

Concentration (per mL)

BPC-157
3 mg
GHK-Cu
10 mg
KPV
3 mg
TB-500
3 mg
Total
19 mg

Per dose (20 units, 0.2 mL)

BPC-157
0.6 mg
GHK-Cu
2.0 mg
KPV
0.6 mg
TB-500
0.6 mg
Total
3.8 mg

Per week (5 doses, Mon-Fri)

BPC-157
3 mg
GHK-Cu
10 mg
KPV
3 mg
TB-500
3 mg
Total
19 mg

Per 6-week course (30 doses)

BPC-157
18 mg
GHK-Cu
60 mg
KPV
18 mg
TB-500
18 mg
Total
114 mg

Doses per 5 mL vial

BPC-157
25
GHK-Cu
25
KPV
25
TB-500
25
Total
25 doses

Vials per 6-week course

BPC-157
1.2
GHK-Cu
1.2
KPV
1.2
TB-500
1.2
Total
Runs into a 2nd vial

Two things jump out of the table. One week of KLOW delivers exactly the per-mL contents of the vial, because five doses of 0.2 mL is 1 mL, so whatever the label says per mL is your weekly intake. And a 5 mL vial holds 25 doses while a 6-week course needs 30, so plan on a second vial before you start rather than discovering the gap in week five.

Dose Per Day and Per Week

The daily dose is one injection of 20 units. There is no loading phase, no ramp, and no split dosing. There is no titration schedule of the kind GLP-1 protocols use. Day one and day thirty are the same 20 units.

On an insulin syringe, 20 units is a short pull. On a standard 1 mL U-100 syringe it is one-fifth of the barrel; on a 0.5 mL syringe it is two-fifths; on a 0.3 mL syringe it is two-thirds. Read the printed markings, not the volume by eye. The difference between 20 units and 10 units is a few millimeters, and under-drawing is the most common self-inflicted dosing error we see in the first week. If you have never drawn from a vial before, How to Take Peptides walks through the whole sequence from swab to sharps container.

Missed a Dose?

Take it when you remember if it is still the same day. If the day has passed, skip it and resume the next scheduled day. Do not double up to catch up. One missed weekday dose in a 30-dose course does not warrant any correction beyond continuing as planned.

Frequency and Cycle Length

Frequency is Monday through Friday. Cycle length is 6 weeks on, then 6 weeks off. If there is still a reason to use it after the off period, a new cycle can begin, and the prescription for that new cycle goes through the same review as the first. KLOW is not a peptide you stay on indefinitely, and the prescription says so in plain words: do not use continuously.

The off period is not a suggestion tacked onto the end. Three of the four components, BPC-157, TB-500, and KPV, have no human safety data at any duration, and GHK-Cu is a copper complex with a long history in topical cosmetics but a much shorter one as an injectable. Time off is the mechanism that keeps cumulative exposure bounded while the evidence catches up. Six weeks on, six weeks off caps you at 26 dosing weeks in a year, or 130 injections.

Two Rules Attached to the Prescription

No NSAIDs during the cycle: no ibuprofen, naproxen, or aspirin, including the versions hiding inside cold and headache combination products. And expect the possibility of brief lightheadedness after a dose; inject sitting down for the first week and stay seated for a few minutes. A temporary metallic taste is also reported occasionally and is not by itself a concern. If lightheadedness lasts past 15 to 20 minutes, if you faint, or if you have swelling of the face or throat, difficulty breathing, or a rapid heartbeat, that is an emergency.

Timing and Placement

Time of day is not specified on the KLOW prescription, and that is deliberate. Nothing in the blend is tied to fasting or to the sleep cycle the way growth hormone secretagogues are. The prescription cares about consistency more than the clock: pick a time you can hit five days a week and keep it. Most patients settle on the morning, mainly because the lightheadedness question is easier to manage before the day starts. Evening works just as well if that is when you are reliably home and sitting down. Weekends are off, and that is the schedule rather than a compromise: Saturday and Sunday you take nothing.

Placement is specified, and it is the instruction that makes KLOW different from most peptides on the catalog. The dose goes subcutaneously, as close to the injury site as possible, in a region with a pinchable fold of fat, never into a tendon, a joint, or muscle. You still rotate within that region each day. The full site map, the injury-to-region matching, and the extremity workarounds are in Where to Inject KLOW, and they are worth ten minutes before your first dose.

What the 80 mg Charts Get Wrong

Search for KLOW dosage and almost every result describes an 80 mg vial: 50 mg GHK-Cu, 10 mg BPC-157, 10 mg TB-500, 10 mg KPV, sold as a powder for what the vendor calls research use. The charts that come with it walk through adding diluent, computing a concentration, and drawing some number of units to land on a target dose. None of that applies to the prescribed vial, for four reasons that are worth spelling out because patients arrive with these numbers in their heads.

The ratio is different. The 80 mg blend runs 5:1:1:1 in favor of GHK-Cu. The prescribed vial runs about 3.3:1:1:1. At any given total dose, the research blend delivers proportionally more copper peptide and less of everything else. A chart built for one ratio cannot describe the other.

The concentration is whatever the buyer made it. With a powder, the milligrams per unit depend entirely on how much diluent went in, which is why those charts spend most of their length on mixing math. The prescribed vial has one concentration, set by the pharmacy and printed on the label. The unit-to-milligram conversion is fixed and already done.

The cycle assumptions are different. Research-blend charts commonly describe a 20 to 30 day run of the vial at a daily dose sized to finish it, and then a repeat. Those numbers come from vial economics, not from a clinical rationale. The prescribed protocol runs 5 days a week for 6 weeks and then stops for 6, which is a mandated rest period the vendor charts do not have.

Nobody reviewed it. A research-use vial has no prescriber, no screening for the conditions that matter with this blend, and no one accountable for what is in it. The prescribed dose at PeRx was proposed by the pharmacy and approved as written by a medical director in July 2026. That does not make it a trial-validated dose, but a physician did review the concentration, the frequency, and the cycle. Where to buy peptides legally goes into the three sourcing lanes in detail.

Who Is and Is Not a Candidate

Dosing only matters if the blend is appropriate for you in the first place, and KLOW carries more exclusions than a single-peptide prescription because it carries four peptides. The screening at PeRx asks about each of them before a provider reviews the order.

Ideal for

Adults recovering from a specific musculoskeletal injury or a procedure who want the full four-component repair blend rather than BPC-157 alone. People managing more than one nagging soft-tissue problem at the same time. Patients who have already completed a BPC-157/TB-500 course and want the added connective-tissue and inflammatory coverage from GHK-Cu and KPV. Anyone who prefers one daily injection over several.

Consider alternatives if

Anyone with active cancer or a recent cancer history, since several of the components act on cell migration and blood vessel growth. Anyone with Wilson disease or a known copper sensitivity, because every dose carries 2 mg of a copper complex. Anyone with an active infection, an autoimmune diagnosis, inflammatory bowel disease, or current use of immunosuppressants, biologics, or systemic corticosteroids: these are the four KPV screening questions and each needs a provider decision. Anyone who cannot go six weeks without NSAIDs. Pregnant or breastfeeding patients, for whom there is no data at all.

What the FDA Votes Changed

Three of the four peptides in KLOW went before the FDA Pharmacy Compounding Advisory Committee on July 23, 2026, and each was recommended for the 503A bulks list by a vote of 8 to 6. BPC-157, KPV, and TB-500 all cleared on the same day. The fourth component was not on the agenda. Injectable GHK-Cu is among the five substances deferred to a second meeting scheduled before the end of February 2027. The full tally, peptide by peptide, is in our write-up of the July panel.

What Did and Did Not Change

A committee recommendation is advisory. As of August 27, 2026, the FDA has not issued a rule adding any of the three to the bulks list, none of the four peptides is an FDA-approved drug, and KLOW itself remains a compounded product prescribed for an individual patient. The votes did not touch dosing. Nobody at the meeting reviewed a KLOW dose, a per-peptide dose, or a cycle length, and the 20-unit protocol is the same after July 24 as it was before.

What the Evidence Supports

The 20-unit dose is a pharmacy protocol, not a number pulled from a dose-finding study, because no dose-finding study of KLOW exists. It is worth being specific about what does exist for each component, since it explains why the protocol is conservative and why the cycle has an off period.

BPC-157 has the largest literature of the four, and nearly all of it is rodent work from a single research group in Zagreb. The published reviews describe consistent effects on tendon, ligament, muscle, and gut healing in animals at doses that do not translate cleanly to a human protocol. Controlled human trials with published results are essentially absent. That is the state of the evidence for the best-studied ingredient in the vial.

Seiwerth S, Rucman R, Turkovic B, et al. "BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing." Current Pharmaceutical Design. 2018;24(18):1972-1989. View study

TB-500 is a synthetic fragment of thymosin beta-4. The human data that exists belongs to the full thymosin beta-4 molecule, which has been through early-phase wound-healing trials. Those results are sometimes quoted as evidence for TB-500, and they are not the same thing. The fragment itself has no published human dosing data.

Treadwell T, Kleinman HK, Crockford D, et al. "The regenerative peptide thymosin β4 accelerates the rate of dermal healing in preclinical animal models and in patients." Annals of the New York Academy of Sciences. 2012;1270:37-44. View study

KPV has a well-cited mechanism paper showing that the tripeptide enters intestinal cells through the PepT1 transporter and dampens inflammatory signaling in cell culture and in mice, and it has zero published human studies by any route. The FDA review that preceded the July vote searched for human data and reported finding none. GHK-Cu is the outlier: it has decades of cosmetic and wound-dressing research behind it, mostly topical, and a review of its gene-expression effects is the usual citation. Injectable human data at 2 mg per day is not something that review contains.

Dalmasso G, Charrier-Hisamuddin L, Nguyen HT, et al. "PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation." Gastroenterology. 2008;134(1):166-178. View study

Pickart L, Margolina A. "Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data." International Journal of Molecular Sciences. 2018;19(7):1987. View study

KLOW Dosage: Common Questions

As prescribed through PeRx, 20 units (0.2 mL) injected subcutaneously once a day, Monday through Friday, for 6 weeks, followed by 6 weeks off. Each dose delivers 0.6 mg BPC-157, 2.0 mg GHK-Cu, 0.6 mg KPV, and 0.6 mg TB-500 from a vial supplied at 3/10/3/3 mg per mL.

3.8 mg of total peptide per day on dosing days, and nothing on Saturday or Sunday. Over a week that is 19 mg, which happens to equal the per-mL contents of the vial because five doses of 0.2 mL add up to 1 mL.

20 units on a U-100 insulin syringe. That is 0.2 mL regardless of whether the syringe is a 0.3, 0.5, or 1 mL model; only the position of the 20 mark on the barrel changes. Draw to the printed marking rather than estimating the volume.

A 5 mL vial holds 25 doses of 0.2 mL. At five doses a week that is five weeks. A full 6-week course needs 30 doses, so it runs into a second vial. The product page lists KLOW at $349 per one-month supply.

The prescription is written for weekdays only, and the weekend break is part of the protocol. Using it seven days a week raises weekly exposure by 40 percent for four peptides that have little or no human safety data. Follow the schedule as written.

No. There is no titration schedule for KLOW and no evidence that a higher dose produces a better result. Doubling the pull on the syringe doubles your exposure to a copper complex and three peptides without human dosing data. If the protocol does not seem to be doing anything after a full cycle, that is a conversation about whether to run a second cycle, not a reason to draw more.

Because they describe a different product. The 80 mg research blend is 50 mg GHK-Cu and 10 mg each of BPC-157, TB-500, and KPV, sold as a powder the buyer mixes. Its charts compute a concentration from the diluent volume and then size a daily dose to finish the vial in 20 to 30 days. The prescribed vial has a fixed concentration set by the pharmacy, a different ratio of components, and a 6-week-on, 6-week-off cycle. The unit numbers from one cannot be applied to the other.

No. The prescribed KLOW protocol is a fixed 20 units for all adult patients. There is no weight-based scaling in the protocol and no published human data from which weight-based dosing could be derived. Candidacy is decided by screening; the dose itself is the same for everyone who qualifies.

No. The advisory committee voted on whether BPC-157, KPV, and TB-500 should be added to the 503A bulks list, and recommended each by 8 to 6. It did not review any dose, and the vote is non-binding. As of August 27, 2026 no rule has been issued, GHK-Cu has not been reviewed yet, and none of the four peptides is FDA approved.

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